Imipramine Treatment of Opiate-Dependent Patients With Depressive Disorders
Author(s) -
Edward V. Nunes,
F M Quitkin,
Stephen J. Donovan,
Deborah A. Deliyannides,
Katja OcepekWelikson,
Teresa Koenig,
Ronald Brady,
Patrick J. McGrath,
George Woody
Publication year - 1998
Publication title -
archives of general psychiatry
Language(s) - English
Resource type - Journals
eISSN - 1538-3636
pISSN - 0003-990X
DOI - 10.1001/archpsyc.55.2.153
Subject(s) - imipramine , placebo , methadone , clinical global impression , abstinence , antidepressant , medicine , depression (economics) , randomized controlled trial , mood , psychiatry , psychology , anesthesia , anxiety , alternative medicine , pathology , economics , macroeconomics
The literature is inconclusive on the role of antidepressant medications in treating drug dependence. Studies have either not focused on depressed patients or have selected patients with depressive disorders based on cross-sectional symptoms rather than a syndromal diagnosis. A clinical trial of an antidepressant was, therefore, conducted on drug-dependent patients with syndromal depression.
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