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Familial Transmission of Substance Use Disorders
Author(s) -
Kathleen R. Merikangas,
Marilyn Stolar,
Denise Stevens,
Joseph L. Goulet,
Martin Preisig,
Brenda T. Fenton,
Heping Zhang,
Stephanie S. O’Malley,
Bruce J. Rounsaville
Publication year - 1998
Publication title -
archives of general psychiatry
Language(s) - English
Resource type - Journals
eISSN - 1538-3636
pISSN - 0003-990X
DOI - 10.1001/archpsyc.55.11.973
Subject(s) - proband , cannabis , family aggregation , spouse , family history , substance abuse , psychiatry , medicine , alcohol use disorder , drug , first degree relatives , clinical psychology , psychology , risk factor , disease , alcohol , genetics , biochemistry , chemistry , sociology , gene , anthropology , mutation , biology
There is increasing evidence that substance use disorders are familial and that genetic factors explain a substantial degree of their familial aggregation. To perform a controlled family study of probands with several different predominant drugs of abuse, including opioids, cocaine, cannabis, and/or alcohol.

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