
Maternal Progestin Intake and Risk of Hypospadias
Author(s) -
Suzan L. Carmichael,
Gary M. Shaw,
Cecile A. Laurent,
Mary S. Croughan,
Richard S. Olney,
Edward J. Lammer
Publication year - 2005
Publication title -
archives of pediatrics and adolescent medicine
Language(s) - English
Resource type - Journals
eISSN - 1538-3628
pISSN - 1072-4710
DOI - 10.1001/archpedi.159.10.957
Subject(s) - hypospadias , medicine , pregnancy , odds ratio , obstetrics , progestin , gynecology , population , case control study , confidence interval , endocrinology , hormone , surgery , genetics , environmental health , biology
Previous studies have suggested that maternal intake of progestins during early pregnancy may be associated with an increased risk of hypospadias. Progesterone and its derivatives are commonly prescribed during early pregnancy, for example, in cases of luteal phase dysfunction and in conjunction with ovulation stimulation drugs.