Incidence of Occult Bacteremia Among Highly Febrile Young Children in the Era of the Pneumococcal Conjugate Vaccine | Zendy

Matthew L. Stoll | Zendy; Lorry G. Rubin | Zendy

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Incidence of Occult Bacteremia Among Highly Febrile Young Children in the Era of the Pneumococcal Conjugate Vaccine

Author(s) -

Matthew L. Stoll,

Lorry G. Rubin

Publication year - 2004

Publication title -

archives of pediatrics and adolescent medicine

Language(s) - English

Resource type - Journals

eISSN - 1538-3628

pISSN - 1072-4710

DOI - 10.1001/archpedi.158.7.671

Subject(s) - medicine , bacteremia , pneumococcal conjugate vaccine , incidence (geometry) , streptococcus pneumoniae , blood culture , confidence interval , pediatrics , pneumococcal infections , emergency department , occult , cohort , cumulative incidence , white blood cell , pneumococcal vaccine , immunology , antibiotics , pathology , biology , physics , optics , psychiatry , microbiology and biotechnology , alternative medicine

The optimal diagnostic approach to and management of well-appearing, highly febrile young children has been a matter of debate owing to the possibility of clinically inapparent, or occult, bacteremia (OB). The most common causative organism of OB is Streptococcus pneumoniae. Universal immunization with a heptavalent pneumococcal conjugate vaccine (PCV7) has recently been implemented, but there are limited data on the impact of this vaccine on the incidence of OB.

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