Expression of Cathelicidin in Human Salivary Glands
Author(s) -
Jeong Su Woo,
Ji Yong Jeong,
You Jin Hwang,
Sung Won Chae,
Soon Jae Hwang,
Heung Man Lee
Publication year - 2003
Publication title -
archives of otolaryngology--head and neck surgery
Language(s) - English
Resource type - Journals
eISSN - 1538-361X
pISSN - 0886-4470
DOI - 10.1001/archotol.129.2.211
Subject(s) - cathelicidin , antimicrobial peptides , biology , salivary gland , sialadenitis , innate immune system , immunology , immune system , microbiology and biotechnology , antimicrobial , biochemistry
Salivary secretions play a critical role in maintaining oral health via innate host defense mechanisms and secretion of secretory IgA. One of the antimicrobial peptides, LL-37, is the only cathelicidin protein that has yet been identified in humans. Cathelicidins are a family of peptides thought to provide an innate defensive barrier against a variety of potential microbial pathogens.
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