Hürthle Cell Tumors | Zendy

Greg Belchetz | Zendy; Carol C. Cheung | Zendy; Jeremy L. Freeman | Zendy; Irving B. Rosen | Zendy; Ian Witterick | Zendy; L. Sylvia | Zendy

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Hürthle Cell Tumors

Author(s) -

Greg Belchetz,

Carol C. Cheung,

Jeremy L. Freeman,

Irving B. Rosen,

Ian Witterick,

L. Sylvia

Publication year - 2002

Publication title -

archives of otolaryngology - head and neck surgery

Language(s) - English

Resource type - Journals

eISSN - 1538-361X

pISSN - 0886-4470

DOI - 10.1001/archotol.128.3.237

Subject(s) - cancer research , pathology , thyroid carcinoma , cell , pathological , gene , medicine , biology , thyroid , genetics

Since ret/PTC gene rearrangements are specific to papillary thyroid carcinoma (PTC), the diagnosis of Hürthle cell PTC (HCPTC) has recently been expanded to include a subset of Hürthle cell tumors (HCTs) that may lack both papillary architecture and/or classic nuclear features but that harbor a ret/PTC gene rearrangement. We hypothesize that such HCPTCs behave in a fashion analogous to other papillary carcinomas, while Hürthle cell carcinomas (HCCs) behave similarly to follicular carcinomas.

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