Open AccessIndividual Monitoring of Aspirin Desensitization
Archives Of Otolaryngology - Head And Neck SurgeryJan Gosepath +32001Journals
Patients with aspirin-sensitive rhinosinusitis, which is frequently associated with intrinsic bronchial asthma, can be desensitized by long-term treatment with oral aspirin. The exact mechanisms of this desensitization remain obscure, but modulations of the eicosanoid pathway occur and can be monitored with the help of a practicable in vitro assay on mixed leukocyte cultures.
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