Open AccessPollen Immunotherapy Inhibits T Helper 1 and 2 Cell Responses, but Suppression of T Helper 2 Cell Response Is a More Important Mechanism Related to the Clinical Efficacy
Author(s) -
Yasushi Kakinoki,
Y. Ohashi,
Yousuke Nakai,
Akane Tanaka,
Yushi Washio
Publication year - 2000
Publication title -
archives of otolaryngology - head and neck surgery
Language(s) - English
Resource type - Journals
eISSN - 1538-361X
pISSN - 0886-4470
DOI - 10.1001/archotol.126.1.63
Subject(s) - immunology , medicine , immunoglobulin e , peripheral blood mononuclear cell , allergy , cytokine , interleukin 4 , interferon gamma , tumor necrosis factor alpha , immunotherapy , interleukin , cryptomeria , immune system , antibody , biology , japonica , biochemistry , botany , in vitro
To investigate the allergen-induced IgE synthesis and cytokine production by peripheral blood mononuclear cells from patients with seasonal allergic rhinitis due to Japanese cedar (Cryptomeria japonica) pollens and to elucidate the immunological mechanisms related to the clinical efficacy of immunotherapy (IT) for seasonal allergic rhinitis.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom