Plasma Levels of MCP-1 and Adiponectin in Obstructive Sleep Apnea Syndrome
Author(s) -
JooHwan Kim,
ChangHoon Lee,
Chan Soon Park,
Byung Guk Kim,
Soo Whan Kim,
Jin Hee Cho
Publication year - 2010
Publication title -
archives of otolaryngology - head and neck surgery
Language(s) - English
Resource type - Journals
eISSN - 1538-361X
pISSN - 0886-4470
DOI - 10.1001/archoto.2010.142
Subject(s) - adiponectin , medicine , obstructive sleep apnea , polysomnography , proinflammatory cytokine , endocrinology , sleep apnea , apnea–hypopnea index , population , body mass index , apnea , inflammation , gastroenterology , obesity , insulin resistance , environmental health
To evaluate the correlation between concentrations of the proinflammatory cytokines monocyte chemotactic protein 1 (MCP-1), adiponectin, interleukin 6 (IL-6), interleukin 8 (IL-8), and tumor necrosis factor (TNF) and patients with obstructive sleep apnea syndrome (OSAS). Repeated apnea attacks in patients with OSAS constitute a hypoxic condition, which induces tissue inflammation by mediation of these proinflammatory cytokines.
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