Relation of Final Intraoperative Parathyroid Hormone Level and Outcome Following Parathyroidectomy | Zendy

Keith S. Heller | Zendy; Sheila Blumberg | Zendy

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Relation of Final Intraoperative Parathyroid Hormone Level and Outcome Following Parathyroidectomy

Author(s) -

Keith S. Heller,

Sheila Blumberg

Publication year - 2009

Publication title -

archives of otolaryngology - head and neck surgery

Language(s) - English

Resource type - Journals

eISSN - 1538-361X

pISSN - 0886-4470

DOI - 10.1001/archoto.2009.155

Subject(s) - medicine , parathyroidectomy , primary hyperparathyroidism , parathyroid hormone , parathyroid adenoma , surgery , adenoma , hyperparathyroidism , urology , retrospective cohort study , calcium

To determine if final intraoperative parathyroid hormone (IOPTH) level predicts those at risk for recurrence after parathyroidectomy. Minimally invasive parathyroid exploration guided by preoperative imaging and IOPTH level is an accepted alternative to bilateral exploration for the treatment of primary hyperparathyroidism (HPT). However, additional enlarged, hypercellular parathyroid glands are present in some patients in whom IOPTH levels fall to normal after excision of a single adenoma. At least 15% of patients are normocalcemic with elevated PTH levels (PPTH) after parathyroidectomy. In these patients, a higher risk of recurrent HPT has been found.

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