Effect of the Y402H Variant in the Complement Factor H Gene on the Incidence and Progression of Age-Related Macular Degeneration | Zendy

Ronald E. Gang | Zendy; Kristine E. Lee | Zendy; Ronald Klein | Zendy; Sudha K. Iyengar | Zendy; Theru A. Sivakumaran | Zendy

Open Access

Effect of the Y402H Variant in the Complement Factor H Gene on the Incidence and Progression of Age-Related Macular Degeneration

Author(s) -

Ronald E. Gang,

Kristine E. Lee,

Ronald Klein,

Sudha K. Iyengar,

Theru A. Sivakumaran

Publication year - 2012

Publication title -

archives of ophthalmology

Language(s) - English

Resource type - Journals

eISSN - 1538-3601

pISSN - 0003-9950

DOI - 10.1001/archophthalmol.2012.693

Subject(s) - macular degeneration , factor h , incidence (geometry) , medicine , hazard ratio , proportional hazards model , risk factor , ophthalmology , immunology , confidence interval , complement system , physics , antibody , optics

To investigate the effect of age, sex, and the Y402H variant in the complement factor H (CFH) gene on the incidence, progression, and regression of age-related macular degeneration (AMD) as well as the effect of these factors and AMD on mortality, using multistate models.

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