In Vivo Assessment of Vesicular Monoamine Transporter Type 2 in Dementia With Lewy Bodies and Alzheimer Disease
Author(s) -
Victor L. Villemagne
Publication year - 2011
Publication title -
archives of neurology
Language(s) - English
Resource type - Journals
eISSN - 1538-3687
pISSN - 0003-9942
DOI - 10.1001/archneurol.2011.142
Subject(s) - dementia with lewy bodies , monoamine neurotransmitter , vesicular monoamine transporter , disease , alzheimer's disease , dementia , in vivo , neuroscience , medicine , biology , pathology , serotonin , genetics , receptor
To assess the diagnostic potential of imaging striatal monoaminergic terminal integrity with the vesicular monoamine transporter type 2 (VMAT2) radioligand (18)F 9-fluropropyl-(+)-dihydrotetrabenazine ([(18)F]AV-133) and positron emission tomography to distinguish dementia with Lewy bodies (DLB) from Alzheimer disease (AD).
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