Open AccessDisorganized Sensorimotor Integration in Mutation-Positive Myoclonus-Dystonia
Author(s) -
Richard J. Beukers,
E.M.J. Foncke,
Johan N. van der Meer,
Aart J. Nederveen,
Michiel B. de Ruiter,
L.J. Bour,
Dick J. Veltman,
Marina A. J. Tijssen
Publication year - 2010
Publication title -
archives of neurology
Language(s) - English
Resource type - Journals
eISSN - 1538-3687
pISSN - 0003-9942
DOI - 10.1001/archneurol.2010.54
Subject(s) - dystonia , functional magnetic resonance imaging , neuroscience , supplementary motor area , motor cortex , myoclonus , psychology , cerebellum , movement disorders , medicine , magnetic resonance imaging , basal ganglia , central nervous system , disease , stimulation , radiology
Myoclonus-dystonia is an autosomal dominantly inherited movement disorder clinically characterized by myoclonic jerks and dystonic postures or movements of the upper body. Functional imaging studies in other, mainly heterogeneous groups of dystonia do agree on dysfunction of the striato-pallido-thalamo-cortical circuit.