Open AccessAssociation of Low Plasma Aβ42/Aβ40 Ratios With Increased Imminent Risk for Mild Cognitive Impairment and Alzheimer Disease
Author(s) -
Neill R. GraffRadford,
Julia Crook,
John A. Lucas,
Bradley F. Boeve,
David S. Knopman,
Robert J. Ivnik,
Glenn E. Smith,
Linda H. Younkin,
Ronald C. Petersen,
Steven G. Younkin
Publication year - 2007
Publication title -
archives of neurology
Language(s) - English
Resource type - Journals
eISSN - 1538-3687
pISSN - 0003-9942
DOI - 10.1001/archneur.64.3.354
Subject(s) - quartile , dementia , medicine , prospective cohort study , confidence interval , alzheimer's disease , apolipoprotein e , disease , cohort , relative risk , cognitive decline , psychology
To develop preventive therapy for Alzheimer disease (AD), it is essential to develop AD-related biomarkers that identify at-risk individuals in the same way that cholesterol levels identify persons at risk for heart disease.