Open AccessClinically Undetected Motor Neuron Disease in Pathologically Proven Frontotemporal Lobar Degeneration With Motor Neuron Disease
Author(s) -
Keith A. Josephs,
Joseph E. Parisi,
David S. Knopman,
Bradley F. Boeve,
Ronald C. Petersen,
Dennis W. Dickson
Publication year - 2006
Publication title -
archives of neurology
Language(s) - English
Resource type - Journals
eISSN - 1538-3687
pISSN - 0003-9942
DOI - 10.1001/archneur.63.4.506
Subject(s) - frontotemporal lobar degeneration , motor neuron , amyotrophic lateral sclerosis , frontotemporal dementia , gliosis , pathology , hippocampal sclerosis , neuroscience , dementia , medicine , pathological , lower motor neuron , disease , psychology , temporal lobe , epilepsy
Frontotemporal lobar degeneration with motor neuron disease (FTLD-MND) is a pathological entity characterized by motor neuron degeneration and frontotemporal lobar degeneration. The ability to detect the clinical signs of dementia and motor neuron disease in pathologically confirmed FTLD-MND has not been assessed.
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