Open AccessNeurofibrillary Tangles Mediate the Association of Amyloid Load With Clinical Alzheimer Disease and Level of Cognitive Function
Author(s) -
David A. Bennett,
Julie A. Schneider,
R. J. Wilson,
Julia L. Bienias,
Steven E. Arnold
Publication year - 2004
Publication title -
archives of neurology
Language(s) - English
Resource type - Journals
eISSN - 1538-3687
pISSN - 0003-9942
DOI - 10.1001/archneur.61.3.378
Subject(s) - dementia , neurofibrillary tangle , alzheimer's disease , tangle , medicine , logistic regression , amyloid (mycology) , cognition , psychology , senile plaques , disease , pathology , neuroscience , mathematics , pure mathematics
To test the hypothesis that the association of amyloid load with clinical Alzheimer disease (AD) and cognitive impairment is mediated through neurofibrillary tangles.
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