Open AccessPlasma Levels of β-Amyloid(1-40), β-Amyloid(1-42), and Total β-Amyloid Remain Unaffected in Adult Patients With Hypercholesterolemia After Treatment With Statins
Author(s) -
Kina Höglund,
Olov Wiklund,
Hugo Vanderstichele,
Oliver Eikenberg,
Eugeen Vanmechelen,
Kaj Blennow
Publication year - 2004
Publication title -
archives of neurology
Language(s) - English
Resource type - Journals
eISSN - 1538-3687
pISSN - 0003-9942
DOI - 10.1001/archneur.61.3.333
Subject(s) - atorvastatin , simvastatin , medicine , statin , cholesterol , amyloid beta , regimen , beta (programming language) , endocrinology , pharmacology , hmg coa reductase , hyperlipidemia , amyloid (mycology) , gastroenterology , disease , chemistry , reductase , pathology , biochemistry , diabetes mellitus , enzyme , computer science , programming language
Epidemiological studies suggest that statins reduce the risk of developing Alzheimer disease. Cell and animal experiments have revealed a connection between cholesterol metabolism and the processing of amyloid precursor protein. To our knowledge, the mechanism for statins in risk reduction of Alzheimer disease is unknown.
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