Induction by Dopamine D1 Receptor Agonist ABT-431 of Dyskinesia Similar to Levodopa in Patients With Parkinson Disease
Author(s) -
Olivier Rascol,
John G. Nutt,
Olivier Blin,
Christopher G. Goetz,
Joel M. Trugman,
C Soubrouillard,
J H Carter,
L. J. Currie,
Nelly Fabre,
Claire Thalamas,
William J. Giardina,
Stephen Wright
Publication year - 2001
Publication title -
archives of neurology
Language(s) - English
Resource type - Journals
eISSN - 1538-3687
pISSN - 0003-9942
DOI - 10.1001/archneur.58.2.249
Subject(s) - levodopa , dyskinesia , parkinson's disease , dopamine , agonist , pharmacology , medicine , dopamine agonist , dopamine receptor , psychology , disease , dopaminergic , receptor
Dyskinesias are a frequent adverse effect of long-term levodopa therapy. The relative contribution of dopamine D(1) and D(2) receptor function to the pathophysiology of levodopa-induced dyskinesias remains a matter of controversy.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom