In This Issue of Archives of Internal Medicine

A ntiphospholipid syndrome is a multisystem disorder characterized by recurrent thromboses and various neuropsychiatric manifestations. In this study, Tektonidou et al examined the presence of cognitive dysfunction in 60 patients with antiphospholipid syndrome and its association with the clinical, laboratory, and cerebral magnetic resonance imaging characteristics. The authors found that cognitive deficits were frequently detected among patients with antiphospholipid syndrome, independent of any history of central nervous system involvement. Livedo reticularis and the presence of white matter lesions on brain magnetic resonance imaging were associated with an increased risk for cognitive dysfunction.