Efficacy of Corticosteroid Therapy in Patients With an Acute Exacerbation of Chronic Obstructive Pulmonary Disease Receiving Ventilatory Support | Zendy

Inmaculada Alía | Zendy; Miguel A. de la Cal | Zendy; Martin Dres | Zendy; A. Abella | Zendy; Ricard Ferrer | Zendy; Francisco Molina | Zendy; Antoni Torres | Zendy; Federico Gordo | Zendy; José Elizalde | Zendy; Raúl de Pablo | Zendy; Alejandro HueteGarcía | Zendy; Antonio R Anzueto | Zendy

Open Access

Efficacy of Corticosteroid Therapy in Patients With an Acute Exacerbation of Chronic Obstructive Pulmonary Disease Receiving Ventilatory Support

Author(s) -

Inmaculada Alía,

Miguel A. de la Cal,

Martin Dres,

A. Abella,

Ricard Ferrer,

Francisco Molina,

Antoni Torres,

Federico Gordo,

José Elizalde,

Raúl de Pablo,

Alejandro HueteGarcía,

Antonio R Anzueto

Publication year - 2011

Publication title -

archives of internal medicine

Language(s) - English

Resource type - Journals

eISSN - 1538-3679

pISSN - 0003-9926

DOI - 10.1001/archinternmed.2011.530

Subject(s) - medicine , mechanical ventilation , copd , exacerbation , intensive care unit , acute exacerbation of chronic obstructive pulmonary disease , placebo , randomized controlled trial , intubation , corticosteroid , population , anesthesia , alternative medicine , environmental health , pathology

Randomized trials assessing the effect of systemic corticosteroids on chronic obstructive pulmonary disease (COPD) exacerbations excluded patients who were mechanically ventilated or admitted to the intensive care unit (ICU). Critically ill patients constitute a population of persons who are prone to develop complications that are potentially associated with the use of corticosteroids (eg, infections, hyperglycemia, ICU-acquired paresis) that could prolong the duration of mechanical ventilation and even increase mortality.

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