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Role of Transfusion in the Development of Urinary Tract–Related Bloodstream Infection
Author(s) -
Mary A.M. Rogers,
N. Blumberg,
Joanna M. Heal,
Latoya Kuhn,
M. Todd Greene,
Emily Shuman,
Carol E. Chenoweth,
Robert S. Chang,
Sanjay Saint
Publication year - 2011
Publication title -
archives of internal medicine
Language(s) - English
Resource type - Journals
eISSN - 1538-3679
pISSN - 0003-9926
DOI - 10.1001/archinternmed.2011.423
Subject(s) - bloodstream infection , urinary system , intensive care medicine , medicine
There is a growing body of evidence that transfusion alters host defenses against infection.1 A meta-analysis of randomized controlled trials demonstrated that a restrictive approach to red blood cell (RBC) transfusion decreases the risk of infection by 24%.2 This evidence has prompted changes in guidelines for the use of RBC transfusion.3 The objective of this investigation was to examine whether transfusion affects the risk of developing a bloodstream infection from a urinary source.

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