Metformin Use and Mortality Among Patients With Diabetes and Atherothrombosis<alt-title>Metformin Use With Diabetes and Atherothrombosis</alt-title>
Author(s) -
Ronan Roussel
Publication year - 2010
Publication title -
archives of internal medicine
Language(s) - English
Resource type - Journals
eISSN - 1538-3679
pISSN - 0003-9926
DOI - 10.1001/archinternmed.2010.409
Subject(s) - metformin , medicine , diabetes mellitus , hazard ratio , confidence interval , creatinine , type 2 diabetes , overweight , renal function , proportional hazards model , body mass index , endocrinology
Metformin is recommended in type 2 diabetes mellitus because it reduced mortality among overweight participants in the United Kingdom Prospective Diabetes Study when used mainly as a means of primary prevention. However, metformin is often not considered in patients with cardiovascular conditions because of concerns about its safety.
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