Familial Defective Apolipoprotein B-100 and Increased Low-Density Lipoprotein Cholesterol and Coronary Artery Calcification in the Old Order Amish
Author(s) -
Haiqing Shen,
Coleen Damcott,
Evadnie Rampersaud,
Toni I. Pollin,
Richard B. Horenstein,
Patrick F. McArdle,
Patricia A. Peyser,
Lawrence F. Bielak,
Wendy S. Post,
Yen-Pei C. Chang,
Kathleen A. Ryan,
Michael Miller,
John A. Rumberger,
Patrick F. Sheedy,
John C. Shelton,
Jeffrey R. O’Connell,
Alan R. Shuldiner,
Braxton D. Mitchell
Publication year - 2010
Publication title -
archives of internal medicine
Language(s) - English
Resource type - Journals
eISSN - 1538-3679
pISSN - 0003-9926
DOI - 10.1001/archinternmed.2010.384
Subject(s) - apolipoprotein b , medicine , odds ratio , single nucleotide polymorphism , cholesterol , coronary artery disease , asymptomatic , endocrinology , genetics , biology , genotype , gene
Elevated low-density lipoprotein cholesterol (LDL-C) levels are a major cardiovascular disease risk factor. Genetic factors are an important determinant of LDL-C levels.
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