Syncope and Its Consequences in Patients With Dementia Receiving Cholinesterase Inhibitors | Zendy

Sudeep S. Gill | Zendy; George Anderson | Zendy; Hadas D. Fischer | Zendy; Chaim M. Bell | Zendy; Ping Li | Zendy; SharonLise T. Normand | Zendy; Paula A. Rochon | Zendy

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Syncope and Its Consequences in Patients With Dementia Receiving Cholinesterase Inhibitors

Author(s) -

Sudeep S. Gill,

George Anderson,

Hadas D. Fischer,

Chaim M. Bell,

Ping Li,

SharonLise T. Normand,

Paula A. Rochon

Publication year - 2009

Publication title -

archives of internal medicine

Language(s) - English

Resource type - Journals

eISSN - 1538-3679

pISSN - 0003-9926

DOI - 10.1001/archinternmed.2009.43

Subject(s) - medicine , bradycardia , hazard ratio , dementia , cholinesterase , comorbidity , hip fracture , confidence interval , adverse effect , syncope (phonology) , population , cohort , anesthesia , heart rate , blood pressure , osteoporosis , disease , environmental health

Cholinesterase inhibitors are commonly prescribed to treat dementia, but their adverse effect profile has received little attention. These drugs can provoke symptomatic bradycardia and syncope, which may lead to permanent pacemaker insertion. Drug-induced syncope may also precipitate fall-related injuries, including hip fracture.

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