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Angiotensin-Converting Enzyme Inhibitors and Cognitive Decline in Older Adults With Hypertension
Author(s) -
Kaycee M. Sink,
Xiaoyan Leng,
Jeff D. Williamson,
Stephen B. Kritchevsky,
Kristine Yaffe,
Lewis H. Kuller,
Sevil Yaşar,
Hal H. Atkinson,
Mike E. Robbins,
Bruce M. Psaty,
David C. Goff
Publication year - 2009
Publication title -
archives of internal medicine
Language(s) - English
Resource type - Journals
eISSN - 1538-3679
pISSN - 0003-9926
DOI - 10.1001/archinternmed.2009.175
Subject(s) - dementia , medicine , hazard ratio , odds ratio , angiotensin converting enzyme , confidence interval , cognitive decline , risk factor , heart failure , blood pressure , disease
Hypertension (HTN) is a risk factor for dementia, and animal studies suggest that centrally active angiotensin-converting enzyme (ACE) inhibitors (those that cross the blood-brain barrier) may protect against dementia beyond HTN control.

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