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Increased Mortality and Cardiovascular Morbidity Associated With Use of Nonsteroidal Anti-inflammatory Drugs in Chronic Heart Failure
Author(s) -
Gunnar Gislason,
Jeppe Nørgaard Rasmussen,
Steen Z. Abildstrøm,
Tina Ken Schramm,
Morten Lock Hansen,
Emil Loldrup Fosbøl,
Rikke Sørensen,
Fredrik Folke,
Pernille Buch,
Niels Gadsbøll,
Søren Rasmussen,
Henrik E. Poulsen,
Lars Køber,
Mette Madsen,
Christian TorpPedersen
Publication year - 2009
Publication title -
archives of internal medicine
Language(s) - English
Resource type - Journals
eISSN - 1538-3679
pISSN - 0003-9926
DOI - 10.1001/archinternmed.2008.525
Subject(s) - medicine , myocardial infarction , hazard ratio , rofecoxib , diclofenac , celecoxib , heart failure , aspirin , proportional hazards model , confidence interval , anesthesia , biochemistry , chemistry , cyclooxygenase , enzyme
Accumulating evidence indicates increased cardiovascular risk associated with nonsteroidal anti-inflammatory drug (NSAID) use, in particular in patients with established cardiovascular disease. We studied the risk of death and hospitalization because of acute myocardial infarction and heart failure (HF) associated with use of NSAIDs in an unselected cohort of patients with HF.

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