Glucocorticoid Receptor Gene and Risk of Cardiovascular Disease | Zendy

Erica L. T. van den Akker | Zendy

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Glucocorticoid Receptor Gene and Risk of Cardiovascular Disease

Author(s) -

Erica L. T. van den Akker

Publication year - 2008

Publication title -

archives of internal medicine

Language(s) - English

Resource type - Journals

eISSN - 1538-3679

pISSN - 0003-9926

DOI - 10.1001/archinternmed.2007.41

Subject(s) - hazard ratio , glucocorticoid receptor , medicine , myocardial infarction , haplotype , population , confidence interval , prospective cohort study , glucocorticoid , cohort study , disease , cardiology , biology , gene , genetics , allele , environmental health

Genetic variants in immunomodulating genes have been suggested to contribute to the risk of cardiovascular disease. Glucocorticoids are important regulators of inflammatory processes and the immune system. Our aim was to determine the contribution of genetic glucocorticoid receptor variants, with different cortisol sensitivities, to the risk of cardiovascular disease.

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