Open AccessEfficacy of Pneumococcal Vaccination in Adults
Author(s) -
Michael J. Fine
Publication year - 1994
Publication title -
archives of internal medicine
Language(s) - English
Resource type - Journals
eISSN - 1538-3679
pISSN - 0003-9926
DOI - 10.1001/archinte.1994.00420230051007
Subject(s) - medicine , pneumococcal pneumonia , vaccination , pneumococcal vaccine , pneumonia , pneumococcal polysaccharide vaccine , odds ratio , randomized controlled trial , pneumococcal infections , vaccine efficacy , incidence (geometry) , pneumococcal disease , confidence interval , streptococcus pneumoniae , immunology , pediatrics , antibiotics , microbiology and biotechnology , biology , physics , optics
Because of the prevalence of pneumococcal pneumonia, the substantial morbidity and mortality associated with many pneumococcal infections, and an increase in the incidence of antibiotic resistance among pneumococcal isolates, considerable efforts for disease prevention have been made using a polyvalent polysaccharide pneumococcal vaccine. Despite numerous clinical trials of the vaccine, its efficacy in the prevention of pneumococcal infections and other clinically relevant medical outcomes in adults remains uncertain.
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