Open AccessGenetic Predisposition, Nongenetic Risk Factors, and Coronary Infarct
Author(s) -
Antonia Trichopoulou,
Nikos Yiannakouris,
Christina Bamia,
Vassiliki Benetou,
Dimitrios Trichopoulos,
José M. Ordovás
Publication year - 2008
Publication title -
archives of internal medicine
Language(s) - English
Resource type - Journals
eISSN - 1538-3679
pISSN - 0003-9926
DOI - 10.1001/archinte.168.8.891
Subject(s) - odds ratio , genetic predisposition , medicine , risk factor , myocardial infarction , confidence interval , cardiology , disease
Using a genetic predisposition score (GPS), additively integrating the associations of 11 polymorphisms with coronary heart disease (CHD), we examined the consequences of the joint presence of a high GPS and nongenetic CHD risk factors.
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