Emergence of HIV-1 Drug Resistance in Previously Untreated Patients Initiating Combination Antiretroviral TreatmentA Comparison of Different Regimen Types | Zendy

Viktor von Wyl | Zendy

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Emergence of HIV-1 Drug Resistance in Previously Untreated Patients Initiating Combination Antiretroviral Treatment<subtitle>A Comparison of Different Regimen Types</subtitle>

Author(s) -

Viktor von Wyl

Publication year - 2007

Publication title -

archives of internal medicine

Language(s) - English

Resource type - Journals

eISSN - 1538-3679

pISSN - 0003-9926

DOI - 10.1001/archinte.167.16.1782

Subject(s) - medicine , regimen , ritonavir , confidence interval , reverse transcriptase inhibitor , gastroenterology , cart , drug resistance , protease inhibitor (pharmacology) , resistance mutation , virology , viral load , human immunodeficiency virus (hiv) , antiretroviral therapy , reverse transcriptase , biology , polymerase chain reaction , mechanical engineering , biochemistry , microbiology and biotechnology , gene , engineering

Standard first-line combination antiretroviral treatment (cART) against human immunodeficiency virus 1 (HIV-1) contains either a nonnucleoside reverse transcriptase inhibitor (NNRTI) or a ritonavir-boosted protease inhibitor (PI/r). Differences between these regimen types in the extent of the emergence of drug resistance on virological failure and the implications for further treatment options have rarely been assessed.

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