A Controlled Trial of Naltrexone Augmentation of Nicotine Replacement Therapy for Smoking Cessation | Zendy

Stephanie S. O’Malley | Zendy; Judith L. Cooney | Zendy; Suchitra KrishnanSarin | Zendy; Joel A. Dubin | Zendy; Sherry A. McKee | Zendy; Ned L. Cooney | Zendy; Amy Blakeslee | Zendy; Boris Meandzija | Zendy; Denise Romano-Dahlgard | Zendy; Ran Wu | Zendy; Robert Makuch | Zendy; Peter Jatlow | Zendy

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A Controlled Trial of Naltrexone Augmentation of Nicotine Replacement Therapy for Smoking Cessation

Author(s) -

Stephanie S. O’Malley,

Judith L. Cooney,

Suchitra KrishnanSarin,

Joel A. Dubin,

Sherry A. McKee,

Ned L. Cooney,

Amy Blakeslee,

Boris Meandzija,

Denise Romano-Dahlgard,

Ran Wu,

Robert Makuch,

Peter Jatlow

Publication year - 2006

Publication title -

archives of internal medicine

Language(s) - English

Resource type - Journals

eISSN - 1538-3679

pISSN - 0003-9926

DOI - 10.1001/archinte.166.6.667

Subject(s) - abstinence , medicine , naltrexone , placebo , nicotine patch , nicotine replacement therapy , smoking cessation , weight gain , randomization , anesthesia , confidence interval , nicotine , odds ratio , randomized controlled trial , psychiatry , body weight , antagonist , receptor , alternative medicine , pathology

Many smokers remain refractory to current therapies, which only partially address weight gain after smoking cessation. Thus, this study evaluated whether naltrexone hydrochloride augmentation of nicotine patch therapy improves smoking abstinence and reduces postcessation weight gain more than nicotine patch therapy alone and at what dose.

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