The Effect of Early, Intensive Statin Therapy on Acute Coronary Syndrome | Zendy

Edward Hulten | Zendy; Jeffrey L. Jackson | Zendy; Kevin Douglas | Zendy; Susan George | Zendy; Todd C. Villines | Zendy

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The Effect of Early, Intensive Statin Therapy on Acute Coronary Syndrome

Author(s) -

Edward Hulten,

Jeffrey L. Jackson,

Kevin Douglas,

Susan George,

Todd C. Villines

Publication year - 2006

Publication title -

archives of internal medicine

Language(s) - English

Resource type - Journals

eISSN - 1538-3679

pISSN - 0003-9926

DOI - 10.1001/archinte.166.17.1814

Subject(s) - medicine , hazard ratio , acute coronary syndrome , randomized controlled trial , statin , coronary artery disease , confidence interval , medline , clinical trial , intensive care medicine , physical therapy , myocardial infarction , political science , law

In addition to well-established secondary prevention benefits for atherosclerotic coronary artery disease, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) are hypothesized to have short-term benefit in acute coronary syndrome (ACS), yet the data are inconsistent, with some trials underpowered to demonstrate therapeutic benefit. Our objective was to determine the effects of early, intensive statin therapy for ACS.

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