Impact of Inflammation on the Relationship Among Alcohol Consumption, Mortality, and Cardiac Events
Author(s) -
Cinzia Maraldi,
Stefano Volpato,
Stephen B. Kritchevsky,
Matteo Cesari,
Elena M. Andresen,
Christiaan Leeuwenburgh,
Tamara B. Harris,
Anne B. Newman,
Alka M. Kanaya,
Karen Johnson,
Nicolas Rodondi,
Marco Pahor
Publication year - 2006
Publication title -
archives of internal medicine
Language(s) - English
Resource type - Journals
eISSN - 1538-3679
pISSN - 0003-9926
DOI - 10.1001/archinte.166.14.1490
Subject(s) - medicine , hazard ratio , confounding , confidence interval , heart failure , proportional hazards model , cardiology , sudden cardiac death
Uncertainty remains about the overall survival benefit of alcohol consumption and the mechanisms underlying the cardioprotective effect of light to moderate alcohol intake. Recent evidence suggests an anti-inflammatory effect of light to moderate alcohol consumption. We investigated the relationship of alcohol intake with all-cause mortality and cardiac events and evaluated whether this relationship is mediated or modified by inflammatory markers.
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