Angiotensin-Converting Enzyme Inhibitors and Change in Aortic Valve Calcium | Zendy

Kevin D. O’Brien | Zendy; Jeffrey L. Probstfield | Zendy; Michael T. Caulfield | Zendy; Khurram Nasir | Zendy; Junichiro Takasu | Zendy; David M. Shavelle | Zendy; Audrey H. Wu | Zendy; Xue-Qiao Zhao | Zendy; Matthew J. Budoff | Zendy

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Angiotensin-Converting Enzyme Inhibitors and Change in Aortic Valve Calcium

Author(s) -

Kevin D. O’Brien,

Jeffrey L. Probstfield,

Michael T. Caulfield,

Khurram Nasir,

Junichiro Takasu,

David M. Shavelle,

Audrey H. Wu,

Xue-Qiao Zhao,

Matthew J. Budoff

Publication year - 2005

Publication title -

archives of internal medicine

Language(s) - English

Resource type - Journals

eISSN - 1538-3679

pISSN - 0003-9926

DOI - 10.1001/archinte.165.8.858

Subject(s) - medicine , odds ratio , confidence interval , cardiology , aortic valve , aortic valve stenosis , angiotensin converting enzyme , surgery , blood pressure

Calcium accumulation in the aortic valve is a hallmark of aortic sclerosis and aortic stenosis. Because lipoproteins, angiotensin-converting enzyme, and angiotensin II colocalize with calcium in aortic valve lesions, we hypothesized an association between angiotensin-converting enzyme inhibitor (ACEI) use and lowered aortic valve calcium (AVC) accumulation, as measured by electron beam computed tomography.

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