Impact of Influenza Vaccination on Seasonal Mortality in the US Elderly Population
Author(s) -
Lone Simonsen,
Thomas A. Reichert,
Cécile Viboud,
William C. Blackwelder,
Robert J. Taylor,
Mark A. Miller
Publication year - 2005
Publication title -
archives of internal medicine
Language(s) - English
Resource type - Journals
eISSN - 1538-3679
pISSN - 0003-9926
DOI - 10.1001/archinte.165.3.265
Subject(s) - vaccination , demography , mortality rate , excess mortality , medicine , pandemic , population , observational study , covid-19 , environmental health , immunology , disease , infectious disease (medical specialty) , sociology
Observational studies report that influenza vaccination reduces winter mortality risk from any cause by 50% among the elderly. Influenza vaccination coverage among elderly persons (> or =65 years) in the United States increased from between 15% and 20% before 1980 to 65% in 2001. Unexpectedly, estimates of influenza-related mortality in this age group also increased during this period. We tried to reconcile these conflicting findings by adjusting excess mortality estimates for aging and increased circulation of influenza A(H3N2) viruses.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom