Risk of Upper Gastrointestinal Hemorrhage in Warfarin Users Treated With Nonselective NSAIDs or COX-2 Inhibitors
Author(s) -
Marisa Battistella
Publication year - 2005
Publication title -
archives of internal medicine
Language(s) - English
Resource type - Journals
eISSN - 1538-3679
pISSN - 0003-9926
DOI - 10.1001/archinte.165.2.189
Subject(s) - medicine , warfarin , rofecoxib , concomitant , celecoxib , odds ratio , upper gastrointestinal bleeding , lower risk , confidence interval , relative risk , surgery , gastroenterology , cyclooxygenase , atrial fibrillation , biochemistry , chemistry , endoscopy , enzyme
Little is known about the risk of upper gastrointestinal (GI) hemorrhage during the concomitant use of warfarin and selective cyclooxygenase (COX)-2 inhibitors. We examined the association between the concomitant use of warfarin and nonselective nonsteroidal anti-inflammatory drugs (NSAIDs) or selective COX-2 inhibitors in older adults hospitalized for upper GI hemorrhage.
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