Open AccessLowering the Intensity of Oral Anticoagulant Therapy
Author(s) -
Marieke Torn,
F.J.M. van der Meer,
Frits R. Rosendaal
Publication year - 2004
Publication title -
archives of internal medicine
Language(s) - English
Resource type - Journals
eISSN - 1538-3679
pISSN - 0003-9926
DOI - 10.1001/archinte.164.6.668
Subject(s) - medicine , atrial fibrillation , incidence (geometry) , confidence interval , cardiology , stroke (engine) , anticoagulant , rate ratio , surgery , anesthesia , mechanical engineering , physics , optics , engineering
Oral anticoagulation is effective in the prevention of arterial thromboembolism. The major drawback of coumarin therapy is the increased risk of hemorrhage. Implementing the optimal intensity of oral anticoagulation, ie, the level at which thromboembolic events are prevented without introducing an excessive bleeding risk, is an important step to improve the safety of oral anticoagulant therapy.
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