A Population-Based Study of the Incidence, Cause, and Severity of Anaphylaxis in the United Kingdom | Zendy

Michael Peng | Zendy; Hershel Jick | Zendy

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A Population-Based Study of the Incidence, Cause, and Severity of Anaphylaxis in the United Kingdom

Author(s) -

Michael Peng,

Hershel Jick

Publication year - 2004

Publication title -

archives of internal medicine

Language(s) - English

Resource type - Journals

eISSN - 1538-3679

pISSN - 0003-9926

DOI - 10.1001/archinte.164.3.317

Subject(s) - medicine , angioedema , anaphylaxis , incidence (geometry) , population , allergy , nasal congestion , dermatology , respiratory distress , pediatrics , anesthesia , surgery , immunology , nose , physics , environmental health , optics

Anaphylaxis is an acute and potentially fatal systemic reaction usually caused by mast cell-mediated release of histamine. Symptoms can vary in onset, appearance, and severity. Some common symptoms include weakness, dizziness, flushing, angioedema, urticaria, nasal congestion, and sneezing. Severe symptoms include upper respiratory tract obstruction, hypotension, vascular collapse associated with angioedema and urticaria, gastrointestinal distress, cardiovascular arrhythmias, and/or arrest.

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