Lack of Efficacy of Acetaminophen in Treating Symptomatic Knee Osteoarthritis
Author(s) -
John P. Case,
Algis J. Baliunas,
Joel A. Block
Publication year - 2003
Publication title -
archives of internal medicine
Language(s) - English
Resource type - Journals
eISSN - 1538-3679
pISSN - 0003-9926
DOI - 10.1001/archinte.163.2.169
Subject(s) - acetaminophen , medicine , diclofenac , osteoarthritis , placebo , analgesic , antipyretic , diclofenac sodium , randomized controlled trial , anesthesia , knee pain , pharmacology , alternative medicine , pathology
Recommendations state that acetaminophen should be used in preference to nonsteroidal anti-inflammatory drugs in the initial treatment of symptomatic osteoarthritis (OA) of the hip or knee, because of lesser toxicity and the pervasive belief that acetaminophen is not only effective in treating OA pain but is of equal analgesic efficacy as nonsteroidal anti-inflammatory drugs.
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