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Antithrombotic Treatment and the Incidence of Angina Pectoris
Author(s) -
Christine Knottenbelt
Publication year - 2002
Publication title -
archives of internal medicine
Language(s) - English
Resource type - Journals
eISSN - 1538-3679
pISSN - 0003-9926
DOI - 10.1001/archinte.162.8.881
Subject(s) - warfarin , aspirin , medicine , myocardial infarction , angina , placebo , unstable angina , cardiology , incidence (geometry) , antithrombotic , atrial fibrillation , physics , alternative medicine , pathology , optics
In primary prevention, anticoagulation with warfarin sodium to an international normalized ratio of 1.5 and 75 mg of aspirin per day each reduced the incidence of coronary heart disease (CHD). Effects on the development of angina pectoris and total CHD (resulting from angina, myocardial infarction, and coronary death) have been assessed, particularly in light of recent evidence that warfarin may have a "durable effect" on CHD through effects on the pathologic condition of the vessel walls involved.

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