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Low-Molecular-Weight and Unfractionated Heparin for Prevention of Venous Thromboembolism in Neurosurgery
Author(s) -
Alfonso Iorio,
Giancarlo Agnelli
Publication year - 2000
Publication title -
archives of internal medicine
Language(s) - English
Resource type - Journals
eISSN - 1538-3679
pISSN - 0003-9926
DOI - 10.1001/archinte.160.15.2327
Subject(s) - medicine , neurosurgery , heparin , randomized controlled trial , venous thromboembolism , odds ratio , low molecular weight heparin , confidence interval , meta analysis , intensive care medicine , surgery , anesthesia , thrombosis
Venous thromboembolism is a common, life-threatening complication in neurosurgery, but prophylaxis with anticoagulant agents has not gained wide acceptance because of concern about intracranial bleeding. We performed a meta-analysis of controlled randomized trials on the efficacy and safety of heparin in the prophylaxis of venous thromboembolism in neurosurgery.

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