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Recurrent and Persistent Coagulopathy Following Pit Viper Envenomation
Author(s) -
Leslie Boyer,
Steven A. Seifert,
Richard F. Clark,
Jude McNally,
Saralyn R. Williams,
Sean Patrick Nordt,
Frank G. Walter,
Richard C. Dart
Publication year - 1999
Publication title -
archives of internal medicine
Language(s) - English
Resource type - Journals
eISSN - 1538-3679
pISSN - 0003-9926
DOI - 10.1001/archinte.159.7.706
Subject(s) - envenomation , antivenom , coagulopathy , medicine , hypofibrinogenemia , snake bites , consumptive coagulopathy , surgery , partial thromboplastin time , viperidae , anesthesia , disseminated intravascular coagulation , viper , fibrinogen , coagulation , venom , ecology , biology
Coagulation abnormalities following crotaline (pit viper) snakebite have traditionally been considered short-lived, but laboratory studies have rarely been reported beyond the first few days of treatment for envenomation. During the course of an antivenom clinical trial, we observed coagulation defects as late as 2 weeks following envenomation.

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