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Maternal Size at Birth and the Development of Hypertension During Pregnancy
Author(s) -
Mark A. Klebanoff,
Niels Jørgen Secher,
Birgitte R. Mednick,
Charlotte Schulsinger
Publication year - 1999
Publication title -
archives of internal medicine
Language(s) - English
Resource type - Journals
eISSN - 1538-3679
pISSN - 0003-9926
DOI - 10.1001/archinte.159.14.1607
Subject(s) - medicine , gestational hypertension , pregnancy , obstetrics , gestation , odds ratio , blood pressure , gestational age , birth weight , population , small for gestational age , pediatrics , genetics , environmental health , biology
Whether individuals who were small at birth are at increased risk of developing cardiovascular disease (the Barker hypothesis) is a topic of great controversy. Although an increased risk has been suggested by several reports, the reports have been criticized for being based on ill-defined populations, for the large numbers of subjects who were unavailable for follow-up, and for inadequate control of socioeconomic status.

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