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Lifestyle, Stress, and Genes in Peptic Ulcer Disease
Author(s) -
Ismo Räihä,
Helena Kemppainen,
Jaakko Kaprio,
Markku Koskenvuo,
L. Sourander
Publication year - 1998
Publication title -
archives of internal medicine
Language(s) - English
Resource type - Journals
eISSN - 1538-3679
pISSN - 0003-9926
DOI - 10.1001/archinte.158.7.698
Subject(s) - concordance , medicine , disease , twin study , cohort , family aggregation , incidence (geometry) , population , epidemiology , helicobacter pylori , cohort study , demography , gastroenterology , heritability , genetics , biology , environmental health , physics , sociology , optics
The familial accumulation of peptic ulcer disease observed in several studies may be attributable to genetic effects, aggregation of environmental exposure (shared environment), or both. The intrafamilial spread of Helicobacter pylori infection has raised the question whether shared environment could explain the familial aggregation of peptic ulcer disease rather than genetic similarity of family members.

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