Open AccessLeukocytoclastic Vasculitis as the Presenting Feature of Dermatitis Herpetiformis
Author(s) -
Elizabeth Naylor
Publication year - 2011
Publication title -
archives of dermatology
Language(s) - English
Resource type - Journals
eISSN - 1538-3652
pISSN - 0003-987X
DOI - 10.1001/archdermatol.2011.293
Subject(s) - dermatitis herpetiformis , medicine , dermatology , leukocytoclastic vasculitis , skin biopsy , pathology , vasculitis , biopsy , disease
Dermatitis herpetiformis is an autoimmune disease typically characterized by pruritic vesicles located on the extensor surfaces. Classic disease consists of neutrophils in the dermal papillae. Additional histopathologic findings include fibrin deposition and edema within the dermal papillae. Subepidermal vesicles also may be present. Direct immunofluorescence demonstrates granular IgA in the dermal papillae.
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