Magnetic Resonance Imaging in Sclerotic-Type Chronic Graft-vs-Host Disease
Author(s) -
Jason A Clark,
Lawrence Yao,
Steven Z. Pavletic,
Michael Krumlauf,
Sandra A. Mitchell,
Maria L. Turner,
Edward W. Cowen
Publication year - 2009
Publication title -
archives of dermatology
Language(s) - English
Resource type - Journals
eISSN - 1538-3652
pISSN - 0003-987X
DOI - 10.1001/archdermatol.2009.78
Subject(s) - medicine , magnetic resonance imaging , graft versus host disease , dermis , fasciitis , fascia , hematopoietic stem cell transplantation , transplantation , subcutaneous tissue , skin biopsy , pathology , connective tissue disease , biopsy , surgery , radiology , disease , autoimmune disease
Sclerotic-type chronic graft-vs-host disease (cGVHD) of the skin is an uncommon but potentially debilitating sequela of allogeneic hematopoietic stem cell transplantation. There is no standardized assessment measure for this form of cGVHD. Because a full-thickness incisional biopsy specimen to the level of the fascia may be needed to make a definitive histologic diagnosis of cGVHD-related fasciitis, a noninvasive technique for the assessment and monitoring of sclerotic-type cGVHD, particularly cGVHD-related fasciitis, would be of potential value.
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