Lenalidomide for the Treatment of Resistant Discoid Lupus Erythematosus
Author(s) -
Asha Shah,
Joerg Albrecht,
Zuleika L. Bonilla-Martinez,
Joyce Okawa,
Mathew Rose,
Misha Rosenbach,
Victoria P. Werth
Publication year - 2009
Publication title -
archives of dermatology
Language(s) - English
Resource type - Journals
eISSN - 1538-3652
pISSN - 0003-987X
DOI - 10.1001/archdermatol.2009.30
Subject(s) - medicine , lenalidomide , discoid lupus erythematosus , dermatology , lupus erythematosus , systemic lupus erythematosus , immunology , antibody , disease , multiple myeloma
Discoid lupus erythematosus (DLE) is a chronic, disfiguring disease that is characterized by scaly, erythematous, disk-shaped patches and plaques followed by atrophy, scarring, and dyspigmentation. It is refractory to standard therapies in a small population of patients. We investigated the use of lenalidomide, a thalidomide analogue, as a novel alternative therapy in 2 cases of refractory DLE and report our results.
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