Open AccessKaposi’s Sarcoma Resolves After Sirolimus Therapy in a Patient With Pemphigus Vulgaris
Author(s) -
Sarika Saggar,
Joshua Zeichner,
Tamu T. Brown,
Robert Phelps,
Steven R. Cohen
Publication year - 2008
Publication title -
archives of dermatology
Language(s) - English
Resource type - Journals
eISSN - 1538-3652
pISSN - 0003-987X
DOI - 10.1001/archderm.144.5.654
Subject(s) - medicine , dapsone , immunosuppression , sirolimus , prednisone , pemphigus vulgaris , azathioprine , maintenance therapy , dermatology , sarcoma , surgery , tacrolimus , regimen , chemotherapy , disease , transplantation , pathology
Iatrogenic Kaposi's sarcoma (KS) has been reported in patients who use immunosuppressive regimens for the treatment of autoimmune disorders, malignant neoplasms, and organ transplant rejection. However, iatrogenic KS in the setting of pemphigus vulgaris (PV) has been infrequently observed. The conventional treatment strategy for iatrogenic KS has focused on reducing immunosuppression, which carries a poor prognosis owing to a substantial risk for exacerbation of the primary disease.
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