Pemphigus Vulgaris Acantholysis Ameliorated by Cholinergic Agonists | Zendy

Vu Thuong Nguyen | Zendy; Juan Arredondo | Zendy; Alexander I. Chernyavsky | Zendy; Mark R. Pittelkow | Zendy; Yasuo Kitajima | Zendy; Sergei A. Grando | Zendy

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Pemphigus Vulgaris Acantholysis Ameliorated by Cholinergic Agonists

Author(s) -

Vu Thuong Nguyen,

Juan Arredondo,

Alexander I. Chernyavsky,

Mark R. Pittelkow,

Yasuo Kitajima,

Sergei A. Grando

Publication year - 2004

Publication title -

archives of dermatology

Language(s) - English

Resource type - Journals

eISSN - 1538-3652

pISSN - 0003-987X

DOI - 10.1001/archderm.140.3.327

Subject(s) - carbachol , acantholysis , pyridostigmine bromide , pemphigus vulgaris , cholinergic , pyridostigmine , medicine , pemphigus , keratinocyte , autoantibody , endocrinology , pharmacology , immunology , myasthenia gravis , chemistry , receptor , in vitro , antibody , biochemistry

Pemphigus vulgaris (PV) is an autoimmune, IgG autoantibody-mediated disease of skin and mucosa leading to progressive blistering and nonhealing erosions. Patients develop autoantibodies to adhesion molecules mediating intercellular adhesion and to keratinocyte cholinergic receptors regulating cell adhesion.

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