Effects of Subantimicrobial-Dose Doxycycline in the Treatment of Moderate Acne | Zendy

Robert A. Skidmore | Zendy; Rodney Kovach | Zendy; Clay Walker | Zendy; John G. Thomas | Zendy; Mark Bradshaw | Zendy; William D. James | Zendy; Christopher Powala | Zendy; Robert Ashley | Zendy

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Effects of Subantimicrobial-Dose Doxycycline in the Treatment of Moderate Acne

Author(s) -

Robert A. Skidmore,

Rodney Kovach,

Clay Walker,

John G. Thomas,

Mark Bradshaw,

William D. James,

Christopher Powala,

Robert Ashley

Publication year - 2003

Publication title -

archives of dermatology

Language(s) - English

Resource type - Journals

eISSN - 1538-3652

pISSN - 0003-987X

DOI - 10.1001/archderm.139.4.459

Subject(s) - medicine , doxycycline , acne , placebo , antibiotics , randomized controlled trial , clinical trial , gastroenterology , surgery , dermatology , pathology , alternative medicine , microbiology and biotechnology , biology

To determine if treatment with subantimicrobial-dose (SD) doxycycline hyclate (20-mg tablets taken twice daily) improved clinical outcome, had any detectable effect on skin flora, led to overgrowth or colonization of skin by opportunistic pathogens, or resulted in an increase in antibiotic resistance by the surface skin microflora in patients with moderate acne compared with placebo.

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